Hybridizing the Triple Helix: A prerequisite for managing wicked issues
نویسندگان
چکیده
منابع مشابه
Macrocyclic scaffold for the collagen triple helix.
[structure: see text] Three strands of natural collagen are linked by covalent bonds prior to their folding into a triple helix. We report on a synthetic collagen in which the strands are pendent on a rigid macrocyclic scaffold of C(3) symmetry. The scaffold confers substantial conformational stability upon the collagen triple helix and makes its folding independent of concentration, both desir...
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Cooperative research centers (CRCs) are a significant and growing “triple helix-based” vehicle for promoting cross sector collaboration, knowledge and technology transfer and ultimately innovation. Although there is a growing social science literature on these organizational structures, the management and “best practice” portion of this literature have tended to emphasize success stories and to...
متن کاملTriple Helix-Forming Oligonucleotide
Triple-helical DNA can be formed by oligonucleotides that bind as third strands of DNA in a sequencespecific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Such triple helix-forming oligonucleotides have been used to inhibit gene expression by blocking transcription factor access to promoter sites in transient expression assays. In an alternative approach to ge...
متن کاملA statistically derived parameterization for the collagen triple-helix.
The triple-helix is a unique secondary structural motif found primarily within the collagens. In collagen, it is a homo- or hetero-tripeptide with a repeating primary sequence of (Gly-X-Y)(n), displaying characteristic peptide backbone dihedral angles. Studies of bulk collagen fibrils indicate that the triple-helix must be a highly repetitive secondary structure, with very specific constraints....
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Dr. Nada Korac-Kakabadse Senior Research Fellow Cranfield School of Management Cranfield, Bedford, NK43 OAL, UK [email protected] Alexander Kouzmin Foundation Chair in Management Graduate School of Management University of Western Sydney, Australia [email protected] Andrew Korac-Kakabadse Professor of International Management Development Cranfield School of Management Cranfie...
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ژورنال
عنوان ژورنال: Financial Accountability & Management
سال: 2020
ISSN: 0267-4424,1468-0408
DOI: 10.1111/faam.12245